US Manufacturers by Wyoming
After searching for bicycle manufacturers in Wyoming, there does not appear to be any major professional large-scale bicycle brands manufacturing complete bikes or frames within the state itself. Wyoming is the least populous U.S. state, which likely discourages major bicycle production facilities from opening up shop there.
However, there could be some small, custom bike builders or specialty shops constructing bespoke bikes on a limited basis within Wyoming that I could not uncover in my initial research. But no sizable or well-known bike manufacturers seem to call the state home currently.